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EMD Serono’s IND Cleared for M5049 for Covid-19 Pneumonia

Will initiate a Phase II randomized trial evaluating the safety and efficacy of M5049 in Covid-19 pneumonia.

By: Contract Pharma

Contract Pharma Staff

EMD Serono, the biopharmaceutical business of Merck KGaA, received clearance from U.S. FDA for its investigational new drug application (IND) for M5049 for the treatment of patients with Covid-19 pneumonia. The company will initiate a Phase II randomized trial evaluating the safety and efficacy of M5049 in this patient population. M5049 is a potentially first-in-class small molecule that blocks the activation of Toll-like receptor (TLR)7 and TLR8, two innate immune sensors that detect single-str...

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